Phospho-B-Raf (Thr401) Recombinant Rabbit Monoclonal Antibody (JJ08-72), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532430-Each-of-1 | In Stock | ₹ 46,413.50 |
PIMA532430 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
Phospho-B-Raf (Thr401)
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P15056, P28028
Gene Symbols
BRAF
Immunogen
Synthetic phospho-peptide corresponding to residues surrounding Thr401 of Human B Raf aa 371-420
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot, Western Blot
Clone
JJ08-72
Conjugate
Unconjugated
Gene
BRAF
Gene Alias
94 kDa B-raf protein, 9930012E13Rik, AA120551, AA387315, AA473386, Braf, B-raf, B-raf protein, B-raf protein isoform 1, B-raf protein isoform 2, B-Raf proto-oncogene serine/threonine-protein kinase, B-Raf proto-oncogene serine/threonine-protein kinase (p94), B-Raf proto-oncogene, serine/threonine kinase, Braf transforming gene, BRAF1, B-RAF1, Braf2, Braf-2, C230098H17, C87398, C-RMIL, D6Ertd631e, FLJ95109, MGC126806, murine sarcoma viral (v-raf) oncogene homolog B1, NS7, p94, Proto-oncogene B-Raf, proto-oncogene c-Rmil, RAFB1, RMIL, rmil serine/threonine-protein kinase, serine/threonine kinase, serine/threonine-protein kinase B-raf, Serine/threonine-protein kinase Rmil, v-raf murine sarcoma viral oncogene homolog B, v-raf murine sarcoma viral oncogene homolog B1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
109880, 114486, 673
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus
- It is activated by somatic point mutation in human cancer, and is thought to play a role in the postsynaptic responses of hippocampal neuron
- This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion
- Mutations in B-Raf have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung
- A pseudogene, which is located on chromosome X, has been identified for B-Raf.