Aurora A Recombinant Rabbit Monoclonal Antibody (ST46-07), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532146-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532146 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
Aurora A
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
O14965, P97477
Gene Symbols
AURKA
Immunogen
Synthetic peptide within Human Aurora A aa 1-50
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Western Blot, Western Blot
Clone
ST46-07
Conjugate
Unconjugated
Gene
AURKA
Gene Alias
Aik, Airk, AIRK1, Ark1, ARK-1, AU019385, AURA, AURAK, AURKA, Aurora 2, aurora A, Aurora A Kinase, aurora family kinase 1, Aurora kinase A, aurora/IP, aurora/IPL1-like kinase, aurora/IPL1-related kinase 1, AURORA2, Aurora-A, aurora-related kinase 1, AW539821, Ayk1, Breast tumor-amplified kinase, BTAK, EC 2.7.11.1, hARK1, IAK, IAK1, Ipl1- and aurora-related kinase 1, IPL1-related kinase, MGC34538, OTTHUMP00000031341, OTTHUMP00000166072, PPP1R47, protein phosphatase 1, regulatory subunit 47, ratAurA, RP5-1167H4.6, sereine threonine kinase, serine/threonine kinase 6, serine/threonine protein kinase 15, serine/threonine protein kinase 6, serine/threonine-protein kinase 15, Serine/threonine-protein kinase 6, serine/threonine-protein kinase 6, aurora kinase A, serine/threonine-protein kinase aurora-A, Serine/threonine-protein kinase Ayk1, STK15, STK6, STK7, Unknown (protein for MGC:134472)
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
20878, 6790
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- AURKA (Aurora A) is a serine/threonine kinase that regulates mitosis by association in vivo with centrosomes
- Overexpression of AURKA is observed in many types of cancer
- Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation
- Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal
- Aurora A is viewed as a potential target for anticancer drug treatment
- Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen.