PIMA533120

Phospho-B-Raf (Thr401) Recombinant Rabbit Monoclonal Antibody (4B9), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA533120-Each-of-1 In Stock ₹ 50,596.50

PIMA533120 - Each of 1

₹ 50,596.50

In Stock

Quantity

1

Base Price: ₹ 50,596.50

GST (18%): ₹ 9,107.37

Total Price: ₹ 59,703.87

Antigen

Phospho-B-Raf (Thr401)

Classification

Recombinant Monoclonal

Concentration

1.3 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

P15056

Gene Symbols

BRAF

Immunogen

A synthesized peptide derived from human Phospho-BRAF (T401)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

ELISA, Immunocytochemistry, Western Blot

Clone

4B9

Conjugate

Unconjugated

Gene

BRAF

Gene Alias

94 kDa B-raf protein, 9930012E13Rik, AA120551, AA387315, AA473386, Braf, B-raf, B-raf protein, B-raf protein isoform 1, B-raf protein isoform 2, B-Raf proto-oncogene serine/threonine-protein kinase, B-Raf proto-oncogene serine/threonine-protein kinase (p94), B-Raf proto-oncogene, serine/threonine kinase, Braf transforming gene, BRAF1, B-RAF1, Braf2, Braf-2, C230098H17, C87398, C-RMIL, D6Ertd631e, FLJ95109, MGC126806, murine sarcoma viral (v-raf) oncogene homolog B1, NS7, p94, Proto-oncogene B-Raf, proto-oncogene c-Rmil, RAFB1, RMIL, rmil serine/threonine-protein kinase, serine/threonine kinase, serine/threonine-protein kinase B-raf, Serine/threonine-protein kinase Rmil, v-raf murine sarcoma viral oncogene homolog B, v-raf murine sarcoma viral oncogene homolog B1

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

673

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

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Description

  • BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus
  • It is activated by somatic point mutation in human cancer, and is thought to play a role in the postsynaptic responses of hippocampal neuron
  • This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion
  • Mutations in B-Raf have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung
  • A pseudogene, which is located on chromosome X, has been identified for B-Raf.