Periostin Recombinant Rabbit Monoclonal Antibody (JA63-40), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532701-Each-of-1 | In Stock | ₹ 46,413.50 |
PIMA532701 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
Periostin
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
Q15063
Gene Symbols
Postn
Immunogen
Synthetic pepride within Human Perilipin-1 aa 11-60
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Western Blot
Clone
JA63-40
Conjugate
Unconjugated
Gene
Postn
Gene Alias
A630052E07Rik, AI747096, fasciclin I-like, Fasciclin-I like, LOW QUALITY PROTEIN: periostin, MGC119510, MGC119511, OSF 2, Osf2, OSF-2, osteoblast specific factor 2, osteoblast specific factor 2 (fasciclin I-like), osteoblast-specific factor 2, PDLPOSTN, peri, periodontal ligament-specific periostin, periostin, periostin variant 1, periostin variant 2, periostin variant 3, periostin variant 4, periostin variant 5, periostin variant 6, periostin variant 7, periostin variant 8, periostin variant 9, periostin, osteoblast specific factor, periostin-like factor, Plf, PN, POSTN, POSTN protein, RP11 412K4.1, RP11-412K4.1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
10631
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Periostin (PN), also designated osteoblast-specific factor 2 (OSF-2), is a disulfide linked protein originally isolated as a osteoblast-specific factor
- Periostin is a secreted protein that binds heparin and functions as a ligand for alpha(V)beta(3) and alpha(V)beta(5) integrins
- In preosteoblasts, Periostin acts as a cell adhesion molecule and plays a role in osteoblast recruitment, spreading and attachment
- Periostin is mainly detected in lower gastrointestinal tract, aorta, stomach, placenta, uterus and breast tissues but is up-regulated in epithelial ovarian tumors and overexpressed in breast cancer
- Expression of Periostin is increased by bone morphogenetic protein (BMP2) and transforming growth factor beta 1(TGF beta 1)
- Periostin contains a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain, which shows homology with the insect protein fasciclin, and a C-terminal domain.