NFkB p50/p105 Monoclonal Antibody (A2-7), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532911-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532911 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
NFkB p50/p105
Classification
Monoclonal
Concentration
2 mg/mL
Formulation
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P19838, P25799
Gene Symbols
NFKB1
Immunogen
Synthetic peptide within Human NF-kB p105/p50 aa 317-366
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgM
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
A2-7
Conjugate
Unconjugated
Gene
NFKB1
Gene Alias
CVID12, DKFZp686C01211, DNA-binding factor KBF1, EBP-1, KBF1, MGC54151, NF kappaB1, NF KB, NFkappaB, NF-kappaB, NF-kappa-B, NF-kappaB p50, NF-kappaB1, NF-kappa-B1 p84/NF-kappa-B1 p98, NF-kappabeta, NF-kB, NFKB1, NF-KB1, NFKB-p105, NFKB-p50, nuclear factor, nuclear factor kappa b, nuclear factor kappa B subunit 1, nuclear factor kappa-B DNA binding subunit, nuclear factor kappaB p50, nuclear factor NF-kappa-B p105 subunit, Nuclear factor NF-kappa-B p50 subunit, nuclear factor of kappa light chain gene enhancer in B-cells 1, p105, nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105, nuclear factor-kappaB p50, p105, p50, p50 subunit of NF kappaB, p50 subunit of NF-kappaB, p50/p105
Host Species
Mouse
Purification Method
Protein L
Regulatory Status
RUO
Gene ID (Entrez)
18033, 4790
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Mouse Monoclonal Antibody NF-kB is a nuclear transcription factor activated by various extra and intracellular stimuli such as cytokines, UV radiation, stress, in injury, and by bacterial and viral products
- It is involved in regulation of various cellular events including cell growth, differentiation, proliferation, apoptosis and inflammation
- NFKB1 (p50), a 50KDa functional sub-unit of NF-kB, is a member of Rel protein family
- It is synthesized as a p105 precursor protein and consists of an N-terminal conserved RHD-region containing nuclear localization signal, DNA-binding and dimerization domains
- NFKB1 (p50) forms homodimers or heterodimerizes with p65, forming the functional NF-kB factor
- NFKB1 (p50) directs the nuclear translocation of NF-kB and is instrumental in its DNA-bidning
- Pathological role of NF-kB has been suggested in AIDS, hematogenic cancer cell metastasis and rheumatoid arthritis.