CD71 (Transferrin Receptor) Recombinant Rabbit Monoclonal Antibody (RM384), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533038-Each-of-1 | In Stock | ₹ 46,947.50 |
PIMA533038 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,947.50
GST (18%): ₹ 8,450.55
Total Price: ₹ 55,398.05
Antigen
CD71 (Transferrin Receptor)
Classification
Recombinant Monoclonal
Concentration
0.1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.
P02786
Gene Symbols
TFRC
Immunogen
A peptide corresponding to the internal region of human CD71.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
RM384
Conjugate
Unconjugated
Gene
TFRC
Gene Alias
2610028K12Rik, AI195355, AI426448, AU015758, CD antigen CD71, CD71, chicken transferrin receptor, E430033M20Rik, I79_000642, IMD46, mammary tumor virus receptor 1, Mtvr1, Mtvr-1, p90, sTfR, T9, TfR, tfR1, TFR2, TFRC, TR, transferrin receptor, transferrin receptor (p90, CD71), transferrin receptor 2, transferrin receptor protein 1, Transferrin receptor protein 1, serum form, Trfr
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
7037
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- Specificity: reacts to Human CD71
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes
- Endosomal acidification leads to iron release
- The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor
- Transferrin receptor is necessary for development of erythrocytes and the nervous system
- Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.