HIF1AN Recombinant Rabbit Monoclonal Antibody (JG37-66), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA534764-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA534764 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
HIF1AN
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q9NWT6
Gene Symbols
HIF1AN
Immunogen
Synthetic peptide within Human HIF1AN aa 1-50
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
JG37-66
Conjugate
Unconjugated
Gene
HIF1AN
Gene Alias
2310046M24Rik; A830014H24Rik; DKFZp762F1811; factor inhibiting HIF1; factor inhibiting HIF-1; FIH; FIH 1; FIH1; FIH-1; FLJ20615; FLJ22027; Hif1an; hypoxia inducible factor 1 alpha subunit inhibitor; hypoxia inducible factor 1 subunit alpha inhibitor; hypoxia inducible factor 1, alpha subunit inhibitor; hypoxia-inducible factor 1, alpha subunit inhibitor; hypoxia-inducible factor 1-alpha inhibitor; Hypoxia-inducible factor asparagine hydroxylase; peptide-aspartate beta-dioxygenase
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
55662
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Form
Liquid
Related Products
Description
- Positive Control: A549, LOVO, SiHa, human prostate cancer tissue
- Hydroxylates HIF-1 alpha at 'Asn-803' in the C-terminal transactivation domain (CAD)
- Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator
- Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases
- Hydroxylates specific Asn residues within ankyrin repeat domains (ARD) of NFKB1, NFKBIA, NOTCH1, ASB4, PPP1R12A and several other ARD-containing proteins
- Also hydroxylates Asp and His residues within ARDs of ANK1 and TNKS2, respectively
- Negatively regulates NOTCH1 activity, accelerating myogenic differentiation
- Positively regulates ASB4 activity, promoting vascular differentiation
- [UniProt]