PIPA5102692

TRAF7 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5102692-Each-of-1 In Stock ₹ 46,502.50

PIPA5102692 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

TRAF7

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TRAF7

Gene Alias

DKFZp586I021; E3 ubiquitin-protein ligase TRAF7; MGC7807; RFWD1; RGD1559653; ring finger and WD repeat domain 1; ring finger and WD repeat domain 1 isoform 1; RING finger and WD repeat-containing protein 1; RING finger protein 119; RING-type E3 ubiquitin transferase TRAF7; RNF119; TNF receptor associated factor 7; TNF receptor-associated factor 7; TNF receptor-associated factor 7, E3 ubiquitin protein ligase; traf7

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

224619, 360491, 84231

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q6Q0C0, Q922B6

Gene Symbols

TRAF7

Immunogen

A synthesized peptide derived from human TRAF7(Accession Q6Q0C0), corresponding to amino acid residues A37-D87.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA5102892

--

Img

Thermo Scientific

PIPA5102656

--

Img

Thermo Scientific

PIPA5103668

--

Img

Thermo Scientific

PIPA5102756

--

Img

Thermo Scientific

PIPA5103036

--

Img

Thermo Scientific

PIPA5103506

--

Img

Thermo Scientific

PIPA5102992

--

Img

Thermo Scientific

PIPA5103372

--

Description

  • Antibody detects endogenous levels of total TRAF7
  • TRAFs are signal transducers for members of TNFR superfamily
  • These are critically involved in activation of MAP3K family members involved in NF-kappaB and JNK activation and apoptosis
  • TRAF7, a novel 670 A
  • A protein, is a human homolog of mouse Traf7 andconsists of an N-terminal RING finger domain, central TRAF domain, a coiled-coil motif and 7 WD40 repeats at the C-terminus
  • It has E3-ubiquitin ligase activity for self-ubiquitination
  • TRAF7 specifically interacts with MEKK3 and mediates MEKK3-induced AP1 and CHOP activation and induces apoptosis through Caspase-independent pathways
  • It is a multifunctional protein involved in sumoylation and negative regulation of c-Myb, thereby regulating proliferation and differentiation of hematopoietic cells.