Phospho-Synaptotagmin 1/2 (Ser309) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5104839-Each-of-1 | In Stock | ₹ 47,036.50 |
PIPA5104839 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,036.50
GST (18%): ₹ 8,466.57
Total Price: ₹ 55,503.07
Antigen
Phospho-Synaptotagmin 1/2 (Ser309)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SYT1
Gene Alias
AW124717, CMS7, FLJ42519, G630098F17Rik, Inositol polyphosphate-binding protein, IP4-binding protein, mKIAA4194, MYSPC, p65, R74640, RATSYNII, SVP65, synaptotagmin 1, synaptotagmin 2, synaptotagmin I, Synaptotagmin II, synaptotagmin-1, Synaptotagmin-2, SYNII, SYT, SYT1, SYT2, SytI, sytII
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
127833, 20979, 20980, 24805, 25716, 6857
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P21579, P21707, P29101, P46096, P46097, Q8N9I0
Gene Symbols
SYT1, SYT2
Immunogen
A synthesized peptide derived from human SYT1(Accession P21579), corresponding to amino acid residues around phosphorylated Ser309.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of Synaptotagmin 1/2 only when phosphorylated at Serine 309
- Synaptotagmins are a large gene family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles
- Calcium binds to Synaptotagmin I which triggers neurotransmitter release at the synapse
- Synaptotagmin II is phosphorylated by WNK1 in a process that regulates calcium-dependent interactions
- Synaptotagmin III is involved in calcium-dependent exocytosis of secretory vesicles in endocrine cells and neurons
- Synaptotagmin IV is expressed in neuronal tissues, and has the highest mRNA levels in the hippocampus.