Phospho-RACGAP1 (Ser387) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105032-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5105032 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Phospho-RACGAP1 (Ser387)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
RACGAP1
Gene Alias
AI227039; AI327394; AKT; Band25; CYK4; GAP; gtl11; GTPase; HsCYK-4; ID; ID-GAP; KIAA1478; Male germ cell RacGap; MGC99656; MgcRacGAP; mKIAA1478; PKB; PKB-ALPHA; PRKBA; protein CYK4 homolg; Protein CYK4 homolog; RAC; Rac GTPase activating protein 1; Rac GTPase-activating protein 1; RAC-ALPHA; Racgap1
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
26934, 29127, 315298
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q9H0H5, Q9WVM1
Gene Symbols
RACGAP1
Immunogen
A synthesized peptide derived from human RACGAP1(Accession Q9H0H5), corresponding to amino acid residues around phosphorylated Ser387.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of RACGAP1 only when phosphorylated at Serine 387
- RAC, a small GTPase in the ras family, regulates the formation of membrane ruffles, lamellipodia and filopodia
- It is involved in cytoskeletal actin organization and transformation
- The p21 activated kinases (PAKs) are direct targets of active Rac and Cdc42 which can induce the assembly of polarized cytoskeletal structures when expressed in fibroblasts
- RAC1 and RAC2 are also essential components of NADPH oxidase, the enzyme responsible for generating free radicals.