Phospho-TOB1 (Ser164) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105180-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5105180 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Phospho-TOB1 (Ser164)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TOB1
Gene Alias
APRO5; APRO6; MGC104792; MGC34446; PIG49; proliferation-inducing gene 49; protein Tob1; Protein Tob1-like protein; TOB; TOB1; transducer of erbB2; Transducer of erbB-2 1; transducer of ERBB2, 1; transducer of ErbB-2.1; Trob; TROB1; Unknown (protein for MGC:134447)
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10140, 170842, 22057
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P50616, Q61471, Q8R5K6
Gene Symbols
TOB1
Immunogen
A synthesized peptide derived from human TOB1(Accession P50616), corresponding to amino acid residues around phosphorylated Ser164.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of TOB1 only when phosphorylated at Ser164
- This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth
- When exogenously expressed, this protein supresses cell growth in tissue culture
- The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase
- Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression
- This protein inhibits T cell proliferation and transcription of cytokines and cyclins
- The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity
- This interaction inhibits interleukin 2 transcription in T cells.