PIPA5105258

TOB1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105258-Each-of-1 In Stock ₹ 46,502.50

PIPA5105258 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

TOB1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TOB1

Gene Alias

APRO5; APRO6; MGC104792; MGC34446; PIG49; proliferation-inducing gene 49; protein Tob1; Protein Tob1-like protein; TOB; TOB1; transducer of erbB2; Transducer of erbB-2 1; transducer of ERBB2, 1; transducer of ErbB-2.1; Trob; TROB1; Unknown (protein for MGC:134447)

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10140, 22057

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P50616, Q61471

Gene Symbols

TOB1

Immunogen

A synthesized peptide derived from human TOB1(Accession P50616), corresponding to amino acid residues V138-G188.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total TOB1
  • This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth
  • When exogenously expressed, this protein supresses cell growth in tissue culture
  • The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase
  • Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression
  • This protein inhibits T cell proliferation and transcription of cytokines and cyclins
  • The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity
  • This interaction inhibits interleukin 2 transcription in T cells.