PIPA5105254

ENSA Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105254-Each-of-1 In Stock ₹ 46,502.50

PIPA5105254 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

ENSA

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ENSA

Gene Alias

1700020C18Rik; 2610007F17Rik; AI451924; Alpha-endosulfine; ARPP-19e; endosulfine alpha; endosulfine-alpha variant 1; endosulfine-alpha variant 3; ENSA

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2029, 56205, 60334

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O43768, P60840, P60841

Gene Symbols

ENSA

Immunogen

A synthesized peptide derived from human ENSA(Accession O43768), corresponding to amino acid residues Y41-L91.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total ENSA
  • The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family
  • This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1
  • ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells
  • This protein is thought to be an endogenous regulator of KATP channels
  • In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes
  • At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.