MilliporeSigma™ anti-Akt, PH Domain Clone: SKB1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ST10881SET-Each-of-1 | In Stock | ₹ 51,972.44 |
ST10881SET - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,972.44
GST (18%): ₹ 9,355.039
Total Price: ₹ 61,327.479
Antigen
Akt, PH Domain
Classification
Monoclonal
Conjugate
Unconjugated
Host Species
Mouse
Quantity
1 Set
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Purified
Applications
Flow Cytometry, Immunoblot, Immunoblot, Immunoprecipitation
Clone
SKB1
Formulation
100μg antibody in 150mM NaCl, 100mM Tris-glycine, 30% glycerol, pH 7.4 and 100μg control lysate.
Immunogen
a recombinant protein consisting of amino acids 1-149 of human Akt 1 fused to GST
Regulatory Status
RUO
Test Specificity
Recognizes the ∽60kDa Akt protein in A431 cells. Useful for the concentration of Akt in samples by immunoprecipitation prior to use in the K-LISA™ Akt Activity Kit. Antibody Target Gene Symbol: AKT1 Target Synonym: AKT, MGC99656, PKB, PKB-ALPHA, PKB/AKT, PRKBA, Protein kinase B, RAC, RAC-ALPHA, Thymoma viral proto-oncogene 1 Entrez Gene Name: v-akt murine thymoma viral oncogene homolog 1
Content And Storage
−20°C
Isotype
IgG
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Description
- Specifically detects Akt, PH Domain Clone: SKB1 in Human, Mouse, Rat samples, and it is validated for Flow Cytometry, Immunoprecipitation, Immuno Blotting Akt (Accession No
- NM_005163) is primarily a cytosolic enzyme that acts as a downstream effector of phosphatidylinositol 3-kinase (PI-3K) activation
- Akt has been shown to be activated by a variety of stimuli, including hematopoetic cytokines, various chemokines, heat shock, hypoxia,hyperosmolarity, integrins, nerve growth factor (NGF), platelet- derived growth factor (PDGF), and T cell receptor signaling
- Suggested to play a role in regulating the balance between cellular mitogenesis and apoptosis
- Akt has been shown to be constitutively active in some human cancers.