Carbonic Anhydrase III Monoclonal Antibody (C2), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Carbonic Anhydrase III
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias
BB219044, CA III, Ca3, CAH3, CAIII, CA-III, CAIII (Muscle), Car3, Car-3, Carbonate dehydratase III, carbonic anhydrase 3, Carbonic anhydrase III, carbonic anhydrase III, muscle specific, carbonic anhydrase-like protein, EC 4.2.1.1, epididymis secretory sperm binding protein Li 167mP, HEL-S-167mP
Gene Symbols
Ca3, Car3
Isotype
IgG2b κ
Purification Method
Protein A/G
Gene
Ca3
Clone
C2
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human, Mouse, Porcine, Rat
Gene Accession No.
P07451, P14141, P16015, Q5S1S4
Gene ID (Entrez)
12350, 494016, 54232, 761
Immunogen
Recombinant Human CA3 protein, Ala2-Lys260 (Accession #P07451)
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
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Description
- Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes
- These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types
- The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle
- A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal
- The gene spans 10
- 3 kb and contains seven exons and six introns.