50-112-2684

EOMES Monoclonal Antibody (WD1928), eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-112-2684-Each-of-1 In Stock ₹ 37,380.00

50-112-2684 - Each of 1

₹ 37,380.00

In Stock

Quantity

1

Base Price: ₹ 37,380.00

GST (18%): ₹ 6,728.40

Total Price: ₹ 44,108.40

Antigen

EOMES

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

O95936

Gene Symbols

Eomes

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100622125, 8320

Content And Storage

4° C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

WD1928

Conjugate

Unconjugated

Gene

Eomes

Gene Alias

C77258; EOMES; eomesodermin; eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; T-box transcription factor; TBR2; TBR-2; T-brain-2

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Porcine

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description: This WD1928 antibody recognizes Eomesodermin (Eomes), also known as T-box brain 2 (TBR2)
  • Eomes is a T-box transcription factor that is highly homologous to T-bet, which is essential during trophoblast development and gastrulation in most vertebrates
  • In the immune system, Eomes controls the differentiation of effector and memory CD8+ T cells, as well as natural killer (NK) cells
  • Expression of Eomes in these cells correlates with high expression of CD122, the common beta-chain of the IL-2R and IL-15R
  • Applications Reported: This WD1928 antibody has been reported for use in immunohistochemical staining of formalin-fixed paraffin embedded tissue sections
  • Applications Tested: This WD1928 antibody has been tested by immunohistochemistry of formalin-fixed paraffin embedded human tissue using low or high pH antigen retrieval and can be used at less than or equal to 5 μg/mL
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Purity: Greater than 90%, as determined by SDS-PAGE
  • Aggregation: Less than 10%, as determined by HPLC
  • Filtration: 0.2 μm post-manufacturing filtered
  • TBR2 is a member of a conserved protein family that shares a common DNA-binding domain, the T-box
  • T-box genes encode transcription factors involved in the regulation of developmental processes
  • A similiar protein disrupted in mice is shown to be essential during trophoblast development and gastrulation
  • TBR2 plays a role in brain development and is required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex.