7188517

AID Monoclonal Antibody (328.8b), Active Motif™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

AID

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

50mM tris HCl with 30% glycerol and 0.035% sodium azide; pH 7.2

Gene Alias

activation induced deaminase; Activation-induced cytidine deaminase; Aicda; Aid; ARP2; CDA2; Cytidine aminohydrolase; epididymis secretory protein Li 284; HEL-S-284; HIGM2; integrated into Burkitt's lymphoma cell line Ramos; Single-stranded DNA cytosine deaminase

Gene Symbols

Aicda

Isotype

IgG2a

Purification Method

Protein G

Product Type

Antibody

Clone

328.8b

Applications

Western Blot

Conjugate

Unconjugated

Host Species

Rat

Target Species

Human, Mouse

Gene Accession No.

Q9GZX7, Q9WVE0

Gene ID (Entrez)

11628, 57379

Immunogen

This AID antbody was raised against a peptide corresponding to amino acids 178-198 of human AID.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

Aicda

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Description

  • This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family
  • The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes
  • Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).