7188650

Mi-2 Monoclonal Antibody (4D8), Active Motif™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Mi-2

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Immunogen

This antibody was raised against a synthetic peptide corresponding to amino acid residues 1641-1662 of Drosophila Mi-2.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Clone

4D8

Applications

Immunofluorescence, Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Host Species

Rat

Target Species

Drosophila

Gene Alias

9530019N15Rik; AA617397; ATP-dependent helicase CHD4; BC005710; CHD4; CHD-4; chromodomain helicase DNA binding protein 4; Chromodomain-helicase-DNA-binding protein 4; D6Ertd380e; Mi-2; Mi-2 autoantigen; Mi-2 autoantigen 218 kDa protein; Mi-2 beta; MI2B; Mi-2b; Mi-2beta; Mi2-beta; mKIAA4075

Isotype

IgG2c

Purification Method

Protein G

Product Type

Antibody

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Description

  • The product of this gene belongs to the SNF2/RAD54 helicase family
  • It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression
  • Patients with dermatomyositis develop antibodies against this protein.