BDB551159
Cyclin E Mouse anti-Human, Unlabeled, Clone: HE12, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB551159-Each-of-1 | In Stock | ₹ 24,564.00 |
BDB551159 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,564.00
GST (18%): ₹ 4,421.52
Total Price: ₹ 28,985.52
Antigen
Cyclin E
Classification
Monoclonal
Conjugate
Unconjugated
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
Applications
Western Blot
Clone
HE12
Host Species
Mouse
Quantity
50 μg
Research Discipline
Cell Biology
Target Species
Human
Isotype
IgG1
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Description
- Cyclins and cyclin-dependent kinases (cdks) are evolutionarily conserved proteins that are essential for cell-cycle control in eukaryotes
- Cyclins (regulatory subunits) bind to cdks (catalytic subunits) to form complexes that regulate the progression of the cell cycle
- These complexes are regulated by activating and inhibitory phosphorylation events, as well as by interactions with small proteins that bind to cyclins, cdks, or cyclin-cdk complexes, e.g., p21 and p27 [Kip1]
- Cyclin E is expressed in G1 and associates with cdk2 to form an active kinase where it plays an important role in the regulation of the G1/S restriction checkpoint in the cell cycle
- Abberant expression of cyclin E has been reported to be associated with the oncogenic transformation of cells
- This antibody has been reported not to cross-react with mouse cyclin E.