MA125524

Thyroid Peroxidase Monoclonal Antibody (MoAb47), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA125524-Each-of-1 In Stock ₹ 49,884.50

MA125524 - Each of 1

₹ 49,884.50

In Stock

Quantity

1

Base Price: ₹ 49,884.50

GST (18%): ₹ 8,979.21

Total Price: ₹ 58,863.71

Antigen

Thyroid Peroxidase

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

tissue culture supernatant with 0.09% sodium azide

Gene Accession No.

P07202

Gene Symbols

TPO

Immunogen

Thyroid Peroxidase purified from human thyroid microsomes.

Regulatory Status

RUO

Gene ID (Entrez)

7173

Content And Storage

4° C, do not freeze

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Clone

MoAb47

Conjugate

Unconjugated

Gene

TPO

Gene Alias

EC 1.11.1; LOW QUALITY PROTEIN: thyroid peroxidase; MSA; TDH2A; thyroid microsomal antigen; thyroid peroxidase; thyroid peroxidase (332 AA); thyroperoxidase; TPO; TPX; TPXEC 1.11.1.8

Host Species

Mouse

Quantity

250 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Recommended positive controls: Thyroid
  • Perform heat mediated retrieval with 1 mM EDTA buffer, pH 8.0
  • We suggest incubation period of 30-60 minutes at room temperature
  • Thyroid Peroxidase is a gene that encodes for a membrane-bound glycoprotein, which functions as an enzyme and plays a crucial role in the proper functioning of the thyroid gland
  • This protein is responsible for the iodination of tyrosine residues in thyroglobulin and the formation of phenoxy-ester between pairs of iodinated tyrosines, which leads to the production of thyroid hormones such as thyroxine and triiodothyronine
  • Mutations in this gene are known to cause several disorders related to thyroid hormone production, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA
  • Several transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants remains undetermined
  • Diseases associated with TPO include Thyroid Dyshormonogenesis 2A and Congenital Hypothyroidism.