MilliporeSigma™ anti-Actin Clone: 2G2,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABT826MI-Each-of-1 | In Stock | ₹ 41,813.98 |
MABT826MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,813.98
GST (18%): ₹ 7,526.516
Total Price: ₹ 49,340.496
Antigen
Actin
Classification
Monoclonal
Conjugate
Unconjugated
Gene Accession No.
P68135
Host Species
Mouse
Purification Method
Purified by ion-exchange chromatography
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Chicken, Frog, Human, Monkey, Mouse, Rabbit, Rat
Form
Purified
Applications
Immunocytochemistry, Western Blot
Clone
2G2
Formulation
Purified mouse monoclonal IgMκ antibody in PBS with 0.05% sodium azide.
Gene Symbols
ACTA1, ACTA
Immunogen
Reconstituted complex of rabbit skeletal muscle actin and calf thymus profilin.
Quantity
100 μL
Research Discipline
Cell Structure
Test Specificity
Clone 2G2 recognizes a tripartite epitope identified in a region of the actin monomer (G-actin) that is not exposed on the surface the filamentous F-actin, but is accessible on the surface of profilin-complexed actin molecule (Gonsior, S.M., et al. (1999). J. Cell Sci. 112 (Pt 6):797-809).
Content And Storage
2°C to 8°C for one year from date of shipment
Isotype
IgM κ
Related Products
Description
- Specifically detects Actin Clone: 2G2 in Chicken, Frog, Human, Monkey, Mouse, Rabbit, Rat samples, and it is validated for Immunocytochemistry, Western Blotting Actin, alpha skeletal muscle (UniProt P68135; also known as Alpha-actin-1) is encoded by the ACTA1 (also known as ACTA) gene (Gene ID 100009506) in Oryctolagus cuniculus (Rabbit) species
- Actins exist in a variety of structural states, depending on the specific ionic conditions or the interaction with ligand proteins
- The oligomeric and polymeric forms that actin molecules assume are dependent on the distinct conformations they adopt
- Research indicates distinct actin conformations/structures in the nucleus and the cytoplasm of different cell types and that their distribution varies in response to external signals
- In additon to serving as the basic building blocks of cytoskeletal microfilaments, actins are involved in multiple nuclear functions and adopt specific conformations that are important for their association with nuclear actin-binding proteins.