Phospho-SHP2 (Tyr542) Recombinant Rabbit Monoclonal Antibody (SN61-01), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532273-Each-of-1 | In Stock | ₹ 46,413.50 |
PIMA532273 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
Phospho-SHP2 (Tyr542)
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P35235, Q06124
Gene Symbols
PTPN11
Immunogen
Synthetic phospho-peptide corresponding to residues surrounding Tyr542 of Human SHP2 aa 511-560
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot, Western Blot
Clone
SN61-01
Conjugate
Unconjugated
Gene
PTPN11
Gene Alias
2700084A17Rik, AW536184, bptp3, CFC, cSH-PTP2, encodes catalytic domain, HCP, HGNC:9644, JMML, METCDS, MGC14433, Noonan syndrome 1, ns1, null, OTTHUMP00000166108, phosphotyrosyl-protein phosphatase, protein tyrosine phosphatase non-receptor type 11, protein tyrosine phosphatase SH-PTP2, protein tyrosine phosphatase, non-receptor type 11, protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1), protein tyrosine phosphatase, non-receptor type 11 S homeolog, protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 2C, protein-tyrosine phosphatase SYP, PTP1C, PTP1D, PTP-1D, ptp-2, PTP2C, PTP-2C, Ptpn11, ptpn11.S, ptpn11-a, ptpn11-b, SAP-2, SH2 domain-containing protein tyrosine phosphatase-2, Shp2, shp-2, SHPTP2, SH-PTP2, SH-PTP2 protein tyrosine phosphatase non-receptor type 11, SH-PTP2 protein tyrosine phosphatase, non-receptor type 11, SH-PTP3, Syp, Tyrosine-protein phosphatase non-receptor type 11, XELAEV_18010676mg
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
19247, 5781
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family
- PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation
- This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates
- This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration
- Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.