PIMA532743

PKC mu Recombinant Rabbit Monoclonal Antibody (JM30-17), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532743-Each-of-1 In Stock ₹ 46,413.50

PIMA532743 - Each of 1

₹ 46,413.50

In Stock

Quantity

1

Base Price: ₹ 46,413.50

GST (18%): ₹ 8,354.43

Total Price: ₹ 54,767.93

Antigen

PKC mu

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

O94806, Q15139, Q5XIS9, Q62101, Q8BZ03, Q8K1Y2, Q9BZL6, Q9WTQ1

Gene Symbols

PRKD1, Prkd2, Prkd3

Immunogen

Synthetic peptide within Human PKC aa 201-250

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Clone

JM30-17

Conjugate

Unconjugated

Gene

PRKD1

Gene Alias

4930557O20Rik, 5730497N19Rik, AI325941, DKFZP586E0820, EPK2, HSPC187, nPKC-D1, nPKC-D2, nPKC-mu, nPKC-nu, PKC mu, PKC nu, PKC u, PKC v, Pkcm, PKCmu, PKC-MU, Pkcnu, PKC-NU, PKCu, PKC-u, PKCv, PKC-v, Pkd, PKD1, PKD2, PKD3, Prkcm, PRKCN, Prkd1, PRKD2, PRKD3, Protein kinase C mu type, protein kinase C nu type, protein kinase C, mu, protein kinase C, nu, protein kinase D, protein kinase D1, protein kinase D2, protein kinase D3, protein kinase EPK2, RGD1308054, Serine/threonine-protein kinase D1, serine/threonine-protein kinase D2, Serine/threonine-protein kinase D3

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

101540, 18760, 23683, 25865, 292658, 313834, 5587, 75292, 85421

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • The PKC family of serine/threonine kinases, including PRKCN (PKD3), is activated intracellularly by signal transduction pathways
  • In humans, at least 12 different PKC polypeptides have been identified
  • These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity
  • PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent
  • PKC mu activation is dependent on the phosphorylation of two activation loop sites, Ser744 and Ser748, via a PKC-dependent signaling pathway.