KPNA2 Recombinant Rabbit Monoclonal Antibody (JM90-33), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532761-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532761 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
KPNA2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P52292, P52293
Gene Symbols
KPNA2
Immunogen
Synthetic peptide within Human KPNA2 aa 41-90
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Western Blot, Western Blot
Clone
JM90-33
Conjugate
Unconjugated
Gene
KPNA2
Gene Alias
2410044B12Rik, IMA2, importin, importin alpha 2, importin alpha P1, Importin subunit alpha-1, importin subunit alpha-2, importin-alpha-P1, IPOA 1, IPOA1, IPOA1 QIP2, karyopherin (importin) alpha 2, Karyopherin A2, karyopherin alpha 2, karyopherin alpha 2 (RAG cohort 1, importin alpha 1), karyopherin subunit alpha 2, karyopherin subunit alpha-2, Kpna2, m-importin-alpha-P1, nuclear import protein, pendulin, Pore targeting complex 58 kDa subunit, PTAC58, QIP2, RAG cohort 1, RAG cohort protein 1, RCH 1, RCH1, SRP 1, SRP1, SRP1 alpha, SRP1alpha, SRP1-alpha
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
16647, 3838, 85245
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- The import of proteins into the nucleus is a process that involves at least 2 steps
- The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex
- Imported proteins require a nuclear localization sequence which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart
- Proteins involved in the first step of nuclear import have been identified in different systems
- These include the Xenopus protein importin and its yeast homolog, SRP1, which bind to the NLS
- KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins
- KPNA2 also may play a role in VJ recombination.