CD51 Recombinant Rabbit Monoclonal Antibody (SC56-07), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532195-Each-of-1 | In Stock | ₹ 53,489.00 |
PIMA532195 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,489.00
GST (18%): ₹ 9,628.02
Total Price: ₹ 63,117.02
Antigen
CD51
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P06756, P43406
Gene Symbols
ITGAV
Immunogen
Synthetic peptide within of Human Integrin alpha V aa 1000-1048
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Western Blot, Western Blot
Clone
SC56-07
Conjugate
Unconjugated
Gene
ITGAV
Gene Alias
1110004F14Rik, 2610028E01Rik, alpha v integrin, antigen identified by monoclonal antibody L230, Cd51, CD61, D430040G12Rik, Dnmt3l-ps1 pseudogene, GP3A, GPIIIa, integrin alpha V, integrin alpha-V, Integrin alpha-V heavy chain, Integrin alpha-V light chain, integrin alphaVbeta3, integrin subunit alpha V, integrin, alpha V, integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51), ITGAV, ITGB3, MSK8, Vitronectin receptor, vitronectin receptor alpha polypeptide (VNRA), vitronectin receptor subunit alpha, VNR, VNRA, VTNR
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
16410, 296456, 3685
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- ITAGV encodes integrin alpha chain V
- Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain
- The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins
- Among the known associating beta chains (beta chains 1,3,5,6, and 8, 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands, the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR)
- In addition to adhesion, many integrins are known to facilitate signal transduction
- The ITGB3 protein product is the integrin beta chain beta 3
- Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain
- A given chain may combine with multiple partners resulting in different integrins
- Integrin beta 3 is found along with the alpha IIb chain in platelets
- Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.