Tet3 Monoclonal Antibody (23B9), Active Motif™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Tet3
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias
B430006D22Rik; BC037432; D230004J03Rik; hCG_40738; KIAA0401; Methylcytosine dioxygenase TET3; MGC22014; probable methylcytosine dioxygenase TET3; putative methylcytosine dioxygenase; Tet methylcytosine deoxygenase 3 isoform; tet methylcytosine dioxygenase 3; tet oncogene family member 3; Tet3
Gene Symbols
TET3
Isotype
IgG2a
Purification Method
Protein G
Product Type
Antibody
Clone
23B9
Applications
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Host Species
Rat
Target Species
Mouse
Gene Accession No.
Q8BG87
Gene ID (Entrez)
194388
Immunogen
This antibody was raised against a recombinant protein corresponding amino acids 976-1521 of mouse Tet3.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
TET3
Related Products
Description
- TET3, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine and is most abundantly expressed in hematopoietic cells
- Unlike the related TET2 protein, mutations in TET3 have not been observed in any myeloid malignancies
- TET3 has been shown to be involved in the demethylation of zygotic DNA before the first mitosis and has been suggested to be involved in the epigenetic reprogramming of the zygotic paternal DNA following natural fertilization and may also contribute to somatic cell nuclear reprogramming during animal cloning.