MA14671

RXRG Monoclonal Antibody (1373), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA14671-Each-of-1 In Stock ₹ 47,481.50

MA14671 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

RXRG

Classification

Monoclonal

Conjugate

Unconjugated

Gene

RXRG

Gene Alias

Nr2b3; Nuclear receptor subfamily 2 group B member 3; retinoic acid receptor RXR-gamma; retinoic X receptor gamma-1; retinoid X receptor; retinoid X receptor gamma; retinoid X receptor, gamma; RXR gamma; RXR gamma-1; RXRC; RXRG

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

6258, 83574

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Clone

1373

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

P48443, Q5BJR8

Gene Symbols

RXRG

Immunogen

Synthetic peptide corresponding to the hinge region of human RXRG conjugated to KLH

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG1

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Description

  • This antibody is predicted to react with bovine, mouse and non-human primate based on 100% sequence homology
  • This antibody is specific for the ∽48 kDa RXR-gamma protein
  • Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005)
  • The Retinoid X Receptors (RXRs) family (RXR alpha, beta, and gamma), preferentially bind 9-cis -RA and regulate gene transcription by forming heterodimers with a second family of RA receptors
  • RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005)
  • RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).