MABF1070MI
MilliporeSigma™ C-Reactive Protein, Mouse, Unlabeled, Clone: 2A8.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABF1070MI-Each-of-1 | In Stock | ₹ 39,160.00 |
MABF1070MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,160.00
GST (18%): ₹ 7,048.80
Total Price: ₹ 46,208.80
Antigen
C-Reactive Protein
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse IgG2bκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
P02741
Immunogen
GST-tagged recombinant human C-reactive protein C-terminal fragment.
Quantity
100 μg
Research Discipline
Inflammation & Immunology
Gene ID (Entrez)
NP_000558
Target Species
Human
Form
Purified
Applications
Western Blot
Clone
2A8.1
Conjugate
Unconjugated
Gene
CRP, PTX1
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 2A8.1 targets an epitope within the C-terminal half of human C-reactive protein.
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG2b κ
Related Products
Description
- C-reactive protein (UniProt P02741) is encoded by the CRP (also known as PTX1) gene (Gene ID 1401) in human
- CRP is the classical acute phase reactant produced by the liver and its circulating concentration increases rapidly in a cytokine-mediated response to tissue injury, infection, and inflammation
- It is an annular, pentameric protein that binds to lysophosphatidylcholine expressed on the surface of dead or dying cells and bacteria in order to activate the complement system via the C1Q complex
- Interleukin-6 (IL-6), produced by macrophages in response to injury and infection, is a major trigger for the synthesis of CRP by the liver
- It plays a major role in early host defense by promoting agglutination, bacterial capsular swelling, phagocytosis, and complement fixation through its calcium-dependent binding to phosphorylcholine
- It can also interact with DNA and histones and scavenge nuclear material released from damaged circulating cells.