IFNAR1 Recombinant Rabbit Monoclonal Antibody (SR45-08), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532006-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532006 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
IFNAR1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P17181, P33896
Gene Symbols
Ifnar1
Immunogen
Synthetic peptide within Human IFNAR1 aa 508-557
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunohistochemistry, Western Blot
Clone
SR45-08
Conjugate
Unconjugated
Gene
Ifnar1
Gene Alias
alpha-type antiviral protein, AVP, beta-type antiviral protein, CD118, CRF2-1, cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, H3K1, Ifar, IFN R1, IFNalpha/beta R1, IFN-alpha/beta receptor 1, IFN-alpha/betaR, IFNalpha/betaR1, IFN-alpha/betaR1, IFN-alpha/betaRalpha, IFNalpha/beta-Ralpha, IFN-alpha-REC, IFNAR, Ifnar1, IFNBR, IFNR1, IFN-R-1, Ifrc, INF-a receptor, Infar, interferon (alpha and beta) receptor 1, interferon (alpha, beta and omega) receptor 1, interferon alpha and beta receptor subunit 1, interferon alpha/beta receptor 1, interferon receptor 1, interferon-alpha/beta receptor 1, interferon-alpha/beta receptor alpha chain, interferon-beta receptor 1, type I interferon receptor 1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
15975, 288264, 3454
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Interferons are widely used therapeutic agents because of their anti tumor and antiviral effects and because of their modulatory effects on the immune system (Biron,2001, Kirkwood, 2002)
- These cytokines produce their effects by binding to the Type 1 Interferon-& Receptor (IFNAR1)
- Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling
- This down regulation is thought to be influenced by phosphorylation of Serine 535 and 539 in the IFNAR1 (Kumar et al., 2003).