Caspase 1 Recombinant Rabbit Monoclonal Antibody (SU40-07), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532137-Each-of-1 | In Stock | ₹ 46,413.50 |
PIMA532137 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
Caspase 1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P29452, P29466, P43527
Gene Symbols
CASP1
Immunogen
Recombinant protein within Human Caspase-1 aa 213-404
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Western Blot, Western Blot
Clone
SU40-07
Conjugate
Unconjugated
Gene
CASP1
Gene Alias
CASP1, CASP-1, CASP1 nirs variant 1, caspase 1, caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase), Caspase1, caspase-1, Caspase-1 subunit p10, Caspase-1 subunit p20, ICE, IL-1 beta-converting enzyme, IL-1B converting enzyme, IL1BC, IL-1BC, IL1BCE, IL1B-convertase, interleukin 1 beta-converting enzyme, interleukin 1, beta, convertase, interleukin 1-B converting enzyme, Interleukin 1beta converting enzyme, interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, p45
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
12362, 25166, 834
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies
- Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens
- Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1-b and IL-18
- Caspase-1 was initially identified as an IL-1-b-converting enzyme; later experiments revealed it to be a mammalian homolog of the C
- elegans cell death gene ced-3 whose overexpression can induce apoptosis in fibroblasts.