Caspase 6 Recombinant Rabbit Monoclonal Antibody (SC56-09), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532201-Each-of-1 | In Stock | ₹ 51,753.50 |
PIMA532201 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,753.50
GST (18%): ₹ 9,315.63
Total Price: ₹ 61,069.13
Antigen
Caspase 6
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
O08738, O35397, P55212
Gene Symbols
Casp6
Immunogen
Synthetic peptide within Human Apolipoprotein E aa 210-249
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
SC56-09
Conjugate
Unconjugated
Gene
Casp6
Gene Alias
apoptotic protease MCH-2, CASP6, CASP-6, caspase 6, caspase 6, apoptosis-related cysteine peptidase, caspase 6, apoptosis-related cysteine protease, caspase-6, Caspase-6 subunit p11, Caspase-6 subunit p18, mCASP-6, MCH2
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
12368, 83584, 839
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates
- Caspases have the ability to cleave after aspartic acid residues
- There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition)
- Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9
- Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.