Caspase 5 Recombinant Rabbit Monoclonal Antibody (SD203-2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532356-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532356 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
Caspase 5
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P51878
Gene Symbols
CASP5
Immunogen
Synthetic peptide within Human Caspase 5 aa 1-50
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
SD203-2
Conjugate
Unconjugated
Gene
CASP5
Gene Alias
CASP5, CASP-5, caspase 5, caspase 5, apoptosis-related cysteine peptidase, caspase 5, apoptosis-related cysteine protease, caspase-5, Caspase-5 subunit p10, Caspase-5 subunit p20, ICE(rel)III, ICE(rel)-III, ICEREL-III, ICH3, ICH-3, Protease ICH-3, protease TY, TY protease
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
838
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies
- Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens
- Members of this subfamily include caspase-1, -4, -5, and -12
- Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1-b and IL-18
- Caspase-5 can interact with caspase-1; both are constituents of the NALP1 inflammasome, a complex that can trigger the cleavage of pro-IL-1-b
- Expression of caspase-5 can be regulated by lipopolysaccharide (LPS) and IFN-gamma.